Reconstruction of Cladoniamide Biosynthesis Reveals Nonenzymatic Routes to Bisindole Diversity
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چکیده
منابع مشابه
Divergent pathways in the biosynthesis of bisindole natural products.
Two molecules of the amino acid L-tryptophan are the biosynthetic precursors to a class of natural products named the "bisindoles." Hundreds of these bisindole molecules have been isolated from natural sources, and many of these molecules have potent medicinal properties. Recent studies have clarified the biosynthetic construction of six bisindole molecules, revealing novel enzymatic mechanisms...
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ژورنال
عنوان ژورنال: ACS Chemical Biology
سال: 2014
ISSN: 1554-8929,1554-8937
DOI: 10.1021/cb500728h